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用3%苯酚水溶液对睾丸鞘膜积液进行硬化治疗。

Sclerotherapy of testicular hydroceles with 3% aqueous phenol.

作者信息

Ozdemir E

机构信息

Department of Urology, Ankara Numune Hospital, Turkey.

出版信息

Hinyokika Kiyo. 1996 Jun;42(6):427-32.

PMID:8741297
Abstract

With the evolution of minimally invasive approaches in medicine, phenol has regained its popularity for the sclerotherapy of testicular hydroceles. Together with reported efficiency and safety of 2.5% phenol in the literature, the recently proved safety of 3% phenol in esophageal variceal sclerotherapy has led us to perform a prospective study to lessen the number of sessions. Sclerotherapy with 3% aqueous phenol was applied on an ambulatory basis to 23 patients with 31 hydroceles, who were over 40 years old and who had no fertility problems. The over-all cure rate was 96% with an average follow-up of 3 years, and 58% of the hydroceles required only one session of treatment. The average number of treatment sessions was 2.2 (range; 1-7). One patient with a history of herniorraphy 10 years earlier, was treated surgically following failure of seven sclerotherapy sessions. Phenol, a sclerosant superior to other conventional agents including tetracyclines, requires neither anesthetics nor prophylactic antibiotics. Our findings indicate that sclerotherapy with 3% phenol is an effective, economical and safe form of therapy for patients with hydrocele.

摘要

随着医学微创方法的发展,苯酚在睾丸鞘膜积液硬化治疗中再度受到青睐。鉴于文献报道2.5%苯酚的有效性和安全性,以及最近证实3%苯酚在食管静脉曲张硬化治疗中的安全性,我们开展了一项前瞻性研究以减少治疗次数。对23例患有31处鞘膜积液、年龄超过40岁且无生育问题的患者,在门诊采用3%苯酚水溶液进行硬化治疗。平均随访3年,总体治愈率为96%,58%的鞘膜积液仅需一次治疗。平均治疗次数为2.2次(范围:1 - 7次)。1例10年前有疝修补术病史的患者,在7次硬化治疗失败后接受了手术治疗。苯酚作为一种优于包括四环素在内的其他传统药物的硬化剂,既不需要麻醉剂也不需要预防性抗生素。我们的研究结果表明,3%苯酚硬化治疗对鞘膜积液患者是一种有效、经济且安全的治疗方式。

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