Ito T, Kurazukuri K, Katoh Y, Morikawa Y
Department of Urology, Itami City Hospital.
Hinyokika Kiyo. 1996 Jun;42(6):461-4.
A 58-year-old male with left renal cell carcinoma and prostatic carcinoma occurring synchronously, is reported. He visited our hospital, because of the high level of serum prostate-specific antigen (PSA) pointed out in a health screening by his company. Prostatic cancer was detected in both lobes of the prostate by needle biopsy specimens and histopathology represented moderately > poorly differentiated adenocarcinoma. Magnetic resonance imaging (MRI) and computed tomography (CT) revealed no cancer invasion beyond the prostate and no lymph node metastasis. Bone scintigram showed no abnormal RI accumulation to bone. Therefore, his prostatic cancer was considered to be at stage B2. Abdominal ultrasound echogram showed the mass lesion in the left kidney. CT and angiogram also demonstrated a left renal tumor. Left radical nephrectomy was performed and histopathology showed a mixed subtype of renal cell carcinoma (stage: pT2b, pN0, pM0). Although 94 cases of double cancers associated with genitourinary organs have been reported in the Japanese literature, only 4 cases of double cancers of renal cell carcinoma and prostatic cancer have been reported.
本文报告了一名58岁男性，其左肾细胞癌与前列腺癌同时发生。他因公司健康筛查中指出的血清前列腺特异性抗原（PSA）水平升高前来我院就诊。经针吸活检标本检测，前列腺两叶均发现前列腺癌，组织病理学显示为中度>低分化腺癌。磁共振成像（MRI）和计算机断层扫描（CT）显示，前列腺外无癌侵犯，无淋巴结转移。骨闪烁造影显示骨骼无异常放射性核素积聚。因此，他的前列腺癌被认为处于B2期。腹部超声检查显示左肾有肿块病变。CT和血管造影也显示左肾有肿瘤。实施了左根治性肾切除术，组织病理学显示为肾细胞癌混合亚型（分期：pT2b，pN0，pM0）。虽然日本文献中已报道94例与泌尿生殖器官相关的双癌病例，但肾细胞癌和前列腺癌双癌仅报道了4例。
