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动脉内注射组织型纤溶酶原激活剂溶栓治疗基底动脉闭塞后急性小脑水肿——病例报告

Acute cerebellar edema following intra-arterial tissue plasminogen activator thrombolysis for basilar artery occlusion--case report.

作者信息

Matsumoto K, Kato A, Kohmura E, Fujinaka T, Fukuhara R

机构信息

Department of Neurosurgery, Hanwa Memorial Hospital, Osaka.

出版信息

Neurol Med Chir (Tokyo). 1996 Jul;36(7):455-7. doi: 10.2176/nmc.36.455.

DOI:10.2176/nmc.36.455
PMID:8741376
Abstract

A 61-year-old male developed acute cerebellar swelling after thrombolytic therapy for basilar artery occlusion. He was treated with intra-arterial tissue plasminogen activator 12 hours following symptomatic onset, and did well in the immediate post-treatment period but deteriorated the next day. Computed tomography demonstrated acute cerebellar edema and hydrocephalus. Suboccipital external decompression and ventricular drainage were performed. He survived and 1 year later he could perform daily activities at home. Computed tomography and angiography are essential to monitor the post-treatment course following thrombolysis of vertebrobasilar occlusive disease.

摘要

一名61岁男性在接受基底动脉闭塞溶栓治疗后出现急性小脑肿胀。症状出现后12小时接受了动脉内组织纤溶酶原激活剂治疗,治疗后即刻情况良好,但第二天病情恶化。计算机断层扫描显示急性小脑水肿和脑积水。进行了枕下外减压和脑室引流。他存活了下来,1年后能够在家中进行日常活动。计算机断层扫描和血管造影对于监测椎基底动脉闭塞性疾病溶栓治疗后的病程至关重要。

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