Revilla B, Martín-Araguz A, Feito N, Moreno-Martínez J M, García de la Rocha M L, Moreno Pérez-Crespo J L, Fernández-Armayor V
Servicio de Neurologia, Hospital Universitario del Aire (Universidad Complutense), Madrid.
Rev Neurol. 1996 Mar;24(127):306-10.
Hiccoughs (singultus) is a habitual physiological phenomenon, the persistence of which might indicate neurological and extraneurological multiple lesions. Its activation involves starting up numerous central and peripheral mechanisms which have yet to be clearly determined. Hiccoughs results from an intermittent myoclonus of the diaphragm, reflex in origin, with unknown authentic cause or physiological significance. It has been suggested that, more than just an abnormal reflex, it could be a type of myoclonus brought on by repeated activity of the 'solitary inspiratory nucleus', by releasing control of the inhibiting-activating upper nervous system activity. We present the case of a patient with uncontrollable hiccoughs lasting over six years as a result of paramedial bilateral thalamic ischaemia (rostral occlusion syndrome of the basilar artery type 1) of cardioembolic origin (auricular fibrillation) secondary to hyperthyroidism.
呃逆(膈肌痉挛)是一种习惯性生理现象,其持续存在可能提示神经和神经外的多种病变。其激活涉及启动众多尚未明确的中枢和外周机制。呃逆是由膈肌间歇性肌阵挛引起的,起源于反射,确切病因和生理意义尚不清楚。有人提出,呃逆不仅仅是一种异常反射,它可能是一种由“孤立吸气核”反复活动导致的肌阵挛类型,是通过解除对抑制 - 激活上神经系统活动的控制而引发的。我们报告一例因甲状腺功能亢进继发心脏栓塞性(心房颤动)起源的双侧丘脑旁正中缺血(基底动脉1型喙侧闭塞综合征)导致呃逆无法控制长达六年以上的患者。