Ng I, Lai K C, Ng M
Department of Pathology, University of Hong Kong, Queen Mary Hospital, Hong Kong.
J Gastroenterol Hepatol. 1996 Mar;11(3):270-4. doi: 10.1111/j.1440-1746.1996.tb00074.x.
Gastric antral vascular ectasia is a rare but important cause of chronic gastrointestinal bleeding. We report five patients in whom endoscopic laser therapy successfully controlled repeated blood loss. The patients were elderly (age range: 61-84 years; mean age: 75 years) and three of them were female. Endoscopically, all patients presented with a characteristic antral appearance of either ecstatic vascular 'stripes' radiating out from the pylorus, or multiple cherry-red spots. In all patients, the gastric mucosal biopsy specimens showed dilatation of the capillaries with focal fibrin thrombi and fibromuscular hyperplasia. Marked improvement of both endoscopic and histological features was achieved with endoscopic laser treatment using Nd-YAG laser photocoagulation. Its importance lies in its recognition and successful treatment with endoscopic laser therapy, which offers an effective and relatively safe alternative to surgery, particularly in elderly patients.
胃窦血管扩张症是慢性胃肠道出血的一种罕见但重要的病因。我们报告了5例经内镜激光治疗成功控制反复失血的患者。这些患者均为老年人（年龄范围：61 - 84岁；平均年龄：75岁），其中3例为女性。在内镜下，所有患者均表现出特征性的胃窦外观，即从幽门放射状分布的扩张血管“条纹”或多个樱桃红点。所有患者的胃黏膜活检标本均显示毛细血管扩张，伴有局灶性纤维蛋白血栓形成和纤维肌增生。使用钕钇铝石榴石激光光凝进行内镜激光治疗后，内镜和组织学特征均有显著改善。其重要性在于对其的认识以及内镜激光治疗的成功应用，这为手术提供了一种有效且相对安全的替代方法，尤其适用于老年患者。
