Salgado L, Paz J E, Castilla E
J Genet Hum. 1977 Mar;25(1):59-63.
Short sternum and widely spaced nipples are recognized clinical findings in Edwards' and Patau's syndromes and in Noonan's, Turner's and renal hypoplasia syndromes, respectively. Sternum length, intermammillary distance, length of trunk and thoracic circumference were measured in 307 consecutive live newborns. Intermammillary distance was found to have the highest partial regression coefficient over sternum length. It seems therefore advisable to consider both parameters in the phenotypic description of syndromes where an abnormal variation of one of them is suspected.
胸骨短小和乳头间距增宽分别是爱德华兹综合征和帕陶综合征以及努南综合征、特纳综合征和肾发育不全综合征的典型临床特征。对307例连续出生的活产新生儿测量了胸骨长度、乳头间距、躯干长度和胸围。发现乳头间距在胸骨长度上具有最高的偏回归系数。因此,在怀疑其中一个参数出现异常变化的综合征的表型描述中,考虑这两个参数似乎是明智的。