Milazzo S, Toussaint P, Proust F, Touzet G, Malthieu D
Department of Ophthalmology, Centre Saint Victor, Amiens, France.
Eur J Ophthalmol. 1996 Jan-Mar;6(1):69-73. doi: 10.1177/112067219600600114.
Pituitary apoplexy is an acute hemorragic or ischemic infarction in pituitary adenomas. The incidence in our series was 6.5%. Clinical diagnosis can often be difficult as the patient is frequently unaware of an existing adenoma (seven out of 11 patients). Therefore, the classic features of the syndrome must be known. They include sudden headaches, impairment of consciousness, endocrinological disturbances and sudden visual deterioration or oculomotor palsies. In this retrospective study from 1987 to 1994 of 14 patients presenting pituitary apoplexy there were 11 cases with visual abnormalities. Oculomotor palsies were more common (82%) than chiasmatic impairment (54.5%) and often revealed pituitary adenoma. CT-Scan and MRI examinations led to diagnosis, and emergency treatment (surgical removal by rhinoseptal approach or less often medical treatment) generally led to a regression of visual disturbances.
垂体卒中是指垂体腺瘤发生急性出血性或缺血性梗死。在我们的病例系列中,其发生率为6.5%。由于患者常常未意识到已存在垂体腺瘤(11例患者中有7例),临床诊断往往困难。因此,必须了解该综合征的典型特征。这些特征包括突发头痛、意识障碍、内分泌紊乱以及突发视力减退或动眼神经麻痹。在这项对1987年至1994年期间14例垂体卒中患者的回顾性研究中,有11例存在视觉异常。动眼神经麻痹比视交叉损害更常见(分别为82%和54.5%),且常常提示垂体腺瘤。CT扫描和磁共振成像检查有助于诊断,紧急治疗(经鼻中隔入路手术切除或较少采用的药物治疗)通常可使视觉障碍消退。