[母乳中两种肠道激素的研究]

[A study on two gut hormones in breast milk].

作者信息

Lu M, Yao F, Guo A

机构信息

Research Unit of Pediatrics, Xu zhou Medical College.

出版信息

Zhonghua Fu Chan Ke Za Zhi. 1995 Oct;30(10):554-6.

PMID:8745504

Abstract

OBJECTIVE

To determine if motilin and gastrin are present in breast milk and to measure their concentrations in human milk and cow milk.

METHODS

The concentration of motilin was measured in 17 samples of human colostrum, 18 samples of human mature milk, 8 samples of cow colostrum and 20 samples of cow mature milk by radioimmunoassay. The concentration of gastrin in human milk was also determined by radioimmunoassay.

RESULTS

Motilin concentration in human colostrum was the highest (416.34 +/- 183.95ng/L), being higher than that in human mature milk (272.91 +/- 148.73ng/L, that in cow colostrum (229.51 +/- 63.68ng/L) and that in cow mature milk (35.46 +/- 16.94ng/L). Evidently the difference in motilin concentration was very significant between human milk and cow milk. The gastrin concentration in human colostrum was 17.20 +/- 11.98ng/L, being higher than that in human mature milk (5.62 +/- 2.33ng/L).

CONCLUSION

Human milk, especially human colostrum, contains high concentrations of motilin and gastrin. Breast feeding, especially early breast feeding, may promote the maturation of the developing gut in neonates and infants.

摘要

目的

确定母乳中是否存在胃动素和胃泌素，并测量它们在人乳和牛乳中的浓度。

方法

采用放射免疫分析法测定17份人初乳、18份人成熟乳、8份牛初乳和20份牛成熟乳中胃动素的浓度。人乳中胃泌素的浓度也通过放射免疫分析法测定。

结果

人初乳中胃动素浓度最高（416.34±183.95ng/L），高于人成熟乳（272.91±148.73ng/L）、牛初乳（229.51±63.68ng/L）和牛成熟乳（35.46±16.94ng/L）。显然，人乳和牛乳中胃动素浓度的差异非常显著。人初乳中胃泌素浓度为17.20±11.98ng/L，高于人成熟乳（5.62±2.33ng/L）。