Faure C
Presse Med. 1995;24(39):1879-81.
In western countries, the sudden infant death syndrome (SIDS) is the leading cause of mortality in infants under one year of age. In an official statement on prevention from the French Ministry of Health, sleeping in the supine position or on the side is recommended for all infants unaffected by a particular medical condition. This clear restrictive recommendation is based on valid epidemiological data but raises questions in the minds of paediatricians and general practitioners since the most recent recommendations for treatment of gastro-oesophageal reflux indicate that the prone position at a 30 degrees angle is the first preventive measure to be taken. We present here an objective view point on this complex problem which others may find helpful in developing a sound approach to each individual case. First it must be emphasized that multiple factors are involved in SIDS. While the confirmed correlation between the supine sleeping position and reduced incidence of SIDS is a valid rationale for population-based preventive measures, it does not indicate any causal relationship. Secondly, epidemiological data is valid for a given geographical area but cannot be extrapolated to other areas without taking into account intercurrent factors such as soft bedding, use of feather-bed quilts, excessive bedroom temperature and passive smoking. The public campaign for the prevention of SIDS should be encouraged as an effective low-cost measure, but both physicians and parents should be aware of its multifactorial nature in order to avoid psychologically catastrophic consequences of the guilt syndrome. For infants with uncomplicated simple gastro-oesophageal reflux, a formerly well-known condition but currently less well tolerated by modern parents, it is essential to explain the physiological nature of the reflux to parents then to propose formula thickeners, antacids or prokinetic agents in particularly symtomatic cases. Sleeping in the 30 degrees prone position should not, in this particular case, be introduced as a preventive measure since the risk induced would probably be greater than the beneficial effect. For complicated reflux, after careful exploration and elimination of other causes of vomiting, treatment should be optimized first, followed by discussion on placing the infant in the 30 degrees prone position which should be considered as a therapeutic tool with the same risk of secondary effects as expected with drugs.
在西方国家,婴儿猝死综合征(SIDS)是一岁以下婴儿死亡的主要原因。在法国卫生部发布的一份关于预防的官方声明中,建议所有未患特殊疾病的婴儿采用仰卧位或侧卧位睡眠。这一明确的限制性建议基于有效的流行病学数据,但在儿科医生和全科医生心中引发了疑问,因为最新的胃食管反流治疗建议表明,30度角的俯卧位是首要采取 的预防措施。我们在此就这个复杂问题提出一种客观观点,其他人可能会发现这有助于针对每个具体案例制定合理的方法。首先必须强调,婴儿猝死综合征涉及多个因素。虽然仰卧睡眠姿势与婴儿猝死综合征发病率降低之间已证实的相关性是基于人群的预防措施的合理依据,但这并不表明存在任何因果关系。其次,流行病学数据在特定地理区域是有效的,但如果不考虑诸如柔软被褥、使用羽绒被、卧室温度过高和被动吸烟等并发因素,就不能推广到其他地区。应鼓励开展预防婴儿猝死综合征的公众宣传活动,因为这是一种有效的低成本措施,但医生和家长都应意识到其多因素性质,以避免内疚综合征带来的心理灾难性后果。对于患有单纯性胃食管反流且无并发症的婴儿,这是一种以前常见但现代家长目前较难接受的情况,向家长解释反流的生理性质,然后在症状特别明显的情况下建议使用配方奶增稠剂、抗酸剂或促动力剂至关重要。在这种特殊情况下,不应将30度俯卧位睡眠作为预防措施引入,因为由此带来的风险可能大于有益效果。对于复杂的反流情况,在仔细排查并排除其他呕吐原因后,应首先优化治疗,然后再讨论将婴儿置于30度俯卧位的问题,应将其视为一种治疗手段,其产生副作用的风险与预期药物相同。