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[引起鱼类细菌性败血症的嗜水气单胞菌的血清群、毒力及溶血活性]

[Serogroups, virulence and hemolytic activity of Aeromon as hydrophila which caused fish bacterial septicaemia].

作者信息

Qian D, Chen Y, Shen J, Shen Z

机构信息

Zhejiang Institute of Freshwater Fisheries, Huzhou.

出版信息

Wei Sheng Wu Xue Bao. 1995 Dec;35(6):460-4.

PMID:8745552
Abstract

A new infected disease called bacterial septicaemia occurred in cyprinid fish throughout China during 1989-1992. A. hydrophila was known as the most important pathogen of this harmful disease. Thirty-three strains of A. hydrophila, most isolated from moribund fishes, were serogrouped by tube-agglutination with rabbit antisera. Most of the isolates could be grouped into two serotypes, TPS-30 and PBJS-76. These two groups could be found not only in Zhejiang province but in other province in south China. It can be concluded that the two serogroups were the main Aeromonas groups caused this fish disease. These isolates were virulent to Carassius auratus, with LD50 values of 10(4) to 10(6). The hemolytic activity ranged from titers of 1/8 to 1/16. No relationship were observed with the hemolytic activity and virulence.

摘要

1989年至1992年期间,一种名为细菌性败血症的新型传染病在中国各地的鲤科鱼类中出现。嗜水气单胞菌被认为是这种有害疾病最重要的病原体。通过试管凝集法用兔抗血清对33株嗜水气单胞菌进行血清分组,这些菌株大多从濒死鱼类中分离得到。大多数分离株可分为两个血清型,TPS - 30和PBJS - 76。这两个组不仅在浙江省被发现,在中国南方的其他省份也有发现。可以得出结论,这两个血清群是导致这种鱼类疾病的主要气单胞菌群。这些分离株对鲫鱼具有毒性,半数致死剂量值为10⁴至10⁶。溶血活性范围为效价1/8至1/16。未观察到溶血活性与毒力之间的关系。

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