Liu Y J, Lu C P
College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
J Vet Med B Infect Dis Vet Public Health. 2004 Jun;51(5):222-4. doi: 10.1111/j.1439-0450.2004.00756.x.
Aeromonas hydrophila and Ichthyophthirius multifiliis are important fish pathogens. To clarify their relationship, two host models, goldfish with trauma and those infected with I. multifiliis, were used to study infection kinetics of A. hydrophila 4332 tagged with plasmid pGFPuv (Ah4332(GFP)). The results showed that in fish suffering from ichthyophthiriosis, the bacterial infection process was accelerated and more persistent than in the other groups. It is suggested that I. multifiliis plays an important role in the infection of A. hydrophila. Mechanical trauma caused by I. multifiliis might act as a portal of entry for A. hydrophila present in the water, thereby facilitating the invasion of bacteria. The ectoparasite might also serve as a vector and reservoir of pathogenic bacteria.
嗜水气单胞菌和多子小瓜虫是重要的鱼类病原体。为阐明它们之间的关系，使用了两种宿主模型，即有创伤的金鱼和感染了多子小瓜虫的金鱼，来研究用质粒pGFPuv标记的嗜水气单胞菌4332（Ah4332(GFP)）的感染动力学。结果表明，在患有小瓜虫病的鱼中，细菌感染过程比其他组加速且更持久。这表明多子小瓜虫在嗜水气单胞菌的感染中起重要作用。多子小瓜虫造成的机械创伤可能作为水中嗜水气单胞菌的进入门户，从而促进细菌的入侵。这种体外寄生虫也可能作为致病细菌的载体和储存库。
