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兔艾美耳球虫的子孢子是如何到达其靶细胞的?

How do sporozoites of rabbit Eimeria species reach their target cells?

作者信息

Pakandl M, Drouet-Viard F, Coudert P

机构信息

Czech Academy of Sciences, Parasitology ustav, Branisovska 31, Ceske Budejovice, Czechoslovakia.

出版信息

C R Acad Sci III. 1995 Dec;318(12):1213-7.

PMID:8745636
Abstract

In all the studies performed on the invasion of the rabbit by sporozoites of 4 Eimeria species it was shown that the sporozoites first penetrate the duodenal epithelium; and then very quickly appear within the IELs of the duodenal epithelium. A few hours later they are found in IELs of their specific site of multiplication. The relationship between an "extraintestinal" route for sporozoites and the IELs homing phenomenon is therefore an exciting hypothesis.

摘要

在所有针对4种艾美耳球虫的子孢子侵入兔子的研究中,结果表明子孢子首先穿透十二指肠上皮;然后很快出现在十二指肠上皮的肠上皮内淋巴细胞(IELs)中。几小时后,它们在其特定增殖部位的IELs中被发现。因此,子孢子的“肠外”途径与IELs归巢现象之间的关系是一个令人兴奋的假说。

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