Hutter C D, Blair M E
City Hospital NHS Trust, Nottingham, UK.
Med Hypotheses. 1996 Jan;46(1):1-4. doi: 10.1016/s0306-9877(96)90225-x.
The epidemiological features of sudden infant death syndrome (cot death) include a peak incidence between 8 and 13 weeks of age, a time of death or conception occurring during the winter months and an excess of deaths in infants born to young multiparous women of low socioeconomic status who smoke. We suggest that, through hypoxia, carbon monoxide in tobacco smoke and in the home exerts a noxious effect on the developing central respiratory control mechanism of the fetal brain which then remains particularly susceptible to further insults in the early postnatal period from infection and hyperthermia, resulting in death from central respiratory dysfunction.
婴儿猝死综合征（摇篮死亡）的流行病学特征包括：发病高峰在8至13周龄之间；死亡或受孕时间发生在冬季；社会经济地位低下且吸烟的年轻经产妇所生婴儿的死亡人数过多。我们认为，烟草烟雾和家庭环境中的一氧化碳通过缺氧对胎儿大脑发育中的中枢呼吸控制机制产生有害影响，而该机制在出生后早期仍特别容易受到感染和体温过高带来的进一步损害，从而导致中枢呼吸功能障碍死亡。
