Puskás C, Kerber S, Weyand M, Schober O
Klink und Poliklinik für Nuklearmedizin, Westfälische Wilhelms-Universi
Nuklearmedizin. 1996 Feb;35(1):31-7.
Actually more than 80% of heart recipients survive the first postoperative year. Early death is mainly caused by rejection and acute infection. After the first year progressive graft atherosclerosis has the greatest impact on prognosis. The review presents scintigraphic methods that have reached clinical impact in the diagnosis of rejection and vascular complications. Immunoscintigraphy with 111In-labelled monoclonal antibodies against myosin proved to be of importance in the diagnosis of rejection especially in long-term follow-up. Perfusion scintigraphy reveals vital and ischemic myocardium. In heart transplant recipients radionuclide ventriculography has been widely replaced by echocardiography. Up to now, the evaluation of increasing nerval integration with 123I-MIBG has not reached clinical impact.
实际上，超过80%的心脏移植受者术后第一年存活。早期死亡主要由排斥反应和急性感染引起。第一年之后，移植血管的进行性动脉粥样硬化对预后影响最大。本文综述了在排斥反应和血管并发症诊断中已产生临床影响的闪烁扫描方法。用111In标记的抗肌球蛋白单克隆抗体进行免疫闪烁扫描在排斥反应诊断中，尤其是长期随访中，已证明具有重要意义。灌注闪烁扫描可显示存活心肌和缺血心肌。在心脏移植受者中，放射性核素心室造影已被超声心动图广泛取代。到目前为止，用123I-MIBG评估神经整合增加尚未产生临床影响。
