Jelinski M D, Ribble C S, Campbell J R, Janzen E D
Department of Herd Medicine and Theriogenology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan.
Can Vet J. 1996 Jan;37(1):23-6.
This study investigated the relationship between abomasal hairballs (trichobezoars) and perforating abomasal ulcers in unweaned beef calves <4 mo of age. The calves enrolled in the study represented routine necropsy submissions to veterinary practitioners in western Canada and to the Western College of Veterinary Medicine. Regardless of the cause of death, each calf was examined for evidence of abomasal ulcers and hairballs. Thirty-two practitioners and the Western College of Veterinary Medicine provided 166 cases for the study; 56 died of perforating ulcers (ulcer calves), and 110 died of causes unrelated to abomasum (non-ulcer calves). The calves ranged in age from 1-90 d; 154 (92.8%) were <61 d of age. Overall, ulcer calves were 2.74 (P = 0.003) times more likely to die with an abomasal hairball than were the nonulcer calves. However, stratifying the calves into 2 age groups, young (<31 d) and old (>30 d), yielded conflicting results. While the young ulcer calves were 3.81 (P = 0.003) times more likely to have a hairball than were the young nonulcer calves, there was no statistically significant relationship (OR = 0.76, P = 0.65) between ulcer and hairballs in the older calves. The authors concluded that the relationship between hairballs and ulcers in the young calves was probably spurious, created by a Berkson's bias. It is unlikely that abomasal hairballs have a significant role in the development of fatal perforating ulcers in beef calves.
本研究调查了4月龄以下未断奶肉用犊牛皱胃毛球（毛粪石）与皱胃穿孔性溃疡之间的关系。参与本研究的犊牛是加拿大西部兽医从业者和西部兽医学院常规尸检的送检对象。无论死亡原因如何，均对每头犊牛进行皱胃溃疡和毛球检查。32名从业者和西部兽医学院为该研究提供了166例病例；56头死于穿孔性溃疡（溃疡犊牛），110头死于与皱胃无关的原因（非溃疡犊牛）。犊牛年龄范围为1至90日龄；154头（92.8%）小于61日龄。总体而言，溃疡犊牛伴有皱胃毛球死亡的可能性是非溃疡犊牛的2.74倍（P = 0.003）。然而，将犊牛分为2个年龄组，即幼龄（小于31日龄）和老龄（大于30日龄），结果相互矛盾。幼龄溃疡犊牛有毛球的可能性是幼龄非溃疡犊牛的3.81倍（P = 0.003），而老龄犊牛的溃疡与毛球之间无统计学显著关系（OR = 0.76，P = 0.65）。作者得出结论，幼龄犊牛毛球与溃疡之间的关系可能是由伯克森偏倚造成的伪关联。皱胃毛球在肉用犊牛致命性穿孔性溃疡的发生中不太可能起重要作用。
