Suppr超能文献

慢性骨髓炎一期治疗方法的改进

Refinements in the one-stage procedure for management of chronic osteomyelitis.

作者信息

Guelinckx P J, Sinsel N K

机构信息

Department of Plastic and Reconstructive Surgery, Hand and Microsurgery, Catholic University Leuven, Belgium.

出版信息

Microsurgery. 1995;16(9):606-11. doi: 10.1002/micr.1920160906.

Abstract

Posttraumatic osteomyelitis remains a frequent problem and requires aggressive surgical treatment to be cured. Radical debridement of all involved soft and hard tissues, obliteration of dead space, and neovascularization of the involved area are obligatory for successful management of the disease. Microvascular free tissue transfer provides the necessary tissue bulk and neovascularization to reconstruct the resulting defect. The transplanted muscle can be optimally mobilized and adjusted in size to obliterate the dead space in contrast to local transposition flaps. This is facilitated by smoothening the bony cavity using a rotating drill system. With an optimal interface between the muscle and the wall of the cavity, small foci of infection can be eliminated. Moreover after free muscle transfer, the optimal environment for secondary bone reconstruction is created. These principles of radical debridement combined with muscle transfer for dead space obliteration, are generally accepted in literature. Nevertheless to achieve this goal several different treatment schedules of repetitive debridements, prolonged antibiotic regimes, and finally various flap transfers have been advocated. We present 16 patients with chronic osteomyelitis treated with radical debridement and immediate free muscle transfer using the latissimus dorsi muscle preferably. Postoperatively an antibiotic course of only 12 days was given. With a mean follow-up of 2 years all patients remained symptom free. Therefore, our results indicate that this long-term problem can be solved by a one-stage procedure using a free flap combined with a short course of antibiotics. However definite conclusions should be reserved for 20 years.

摘要

创伤后骨髓炎仍然是一个常见问题,需要积极的手术治疗才能治愈。对所有受累的软组织和硬组织进行彻底清创、消灭死腔以及使受累区域重新血管化,是成功治疗该疾病的必要条件。游离微血管组织移植可提供必要的组织量并实现血管再生,以修复由此产生的缺损。与局部转移皮瓣相比,移植的肌肉可以得到最佳的活动并调整大小以消除死腔。使用旋转钻孔系统使骨腔光滑有助于实现这一点。通过在肌肉与腔壁之间形成最佳界面,可消除小的感染灶。此外,在游离肌肉移植后,可为二期骨重建创造最佳环境。彻底清创结合肌肉移植以消除死腔的这些原则,在文献中已被普遍接受。然而,为实现这一目标,人们提倡了几种不同的治疗方案,包括重复清创、延长抗生素疗程以及最终进行各种皮瓣转移。我们报告了16例慢性骨髓炎患者,采用彻底清创并立即进行游离肌肉移植,最好使用背阔肌。术后仅给予12天的抗生素疗程。平均随访2年,所有患者均无症状。因此,我们的结果表明,这个长期问题可以通过使用游离皮瓣结合短疗程抗生素的一期手术来解决。然而,确切的结论应保留到20年之后。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验