结直肠癌和腺瘤性息肉患者的血清胃泌素水平：一项前瞻性研究。
Serum gastrin levels in patients with colorectal cancer and adenomatous polyps: a prospective study.
作者信息
Mihas A A, Maliakkal R J, Shueke M, Achord J L
出版信息
Res Commun Mol Pathol Pharmacol. 1995 Nov;90(2):301-4.
PMID:8747797
Abstract
Serum gastrin levels were measured by radioimmunoassay in 62 patients with colorectal neoplasms (40 with adenomatous polyps and 22 with cancer) and 40 controls. Fasting serum gastrin in both the polyp (73.93 +/- 6.5 pg/ml) and the cancer (99 +/- 19.7 pg/ml) groups was significantly higher than those of the control group (42.65 +/- 2.2 pg/ml). These findings suggest that hypergastrinemia may be an etiologic factor in colorectal neoplasia.
摘要
采用放射免疫分析法测定了62例结直肠肿瘤患者（40例腺瘤性息肉患者和22例癌症患者）及40例对照者的血清胃泌素水平。息肉组（73.93±6.5 pg/ml）和癌症组（99±19.7 pg/ml）的空腹血清胃泌素水平均显著高于对照组（42.65±2.2 pg/ml）。这些发现提示高胃泌素血症可能是结直肠肿瘤形成的一个病因学因素。
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