脂类-蛋白质相互作用：去污剂与L-谷氨酸脱氢酶的结合

Lipid-protein interactions: detergent binding to L-glutamic acid dehydrogenase.

作者信息

Kempner D H, Johnson B J

出版信息

J Pharm Sci. 1977 Jun;66(6):876-7. doi: 10.1002/jps.2600660638.

Abstract

A nonionic detergent was found to bind to the enzyme L-glutamic acid dehydrogenase [L-glutamate:nicotinamide adenine dinucleotide phosphate oxidoreductase (deaminating) EC 1.4.1.3]. The amount bound was 17 moles of detergent/mole of enzyme, which, however, was not sufficient for the enzyme to be included in a detergent micelle.

摘要

发现一种非离子洗涤剂能与L-谷氨酸脱氢酶[L-谷氨酸：烟酰胺腺嘌呤二核苷酸磷酸氧化还原酶（脱氨基），EC 1.4.1.3]结合。结合的洗涤剂量为每摩尔酶17摩尔洗涤剂，然而，这一量不足以使酶被纳入洗涤剂胶束中。