Poyurovsky M, Kreinin A, Modai I, Weizman A
Tirat Carmel Mental Health Center, Haifa, Tel Aviv University, Israel.
Int Clin Psychopharmacol. 1995 Nov;10(4):261-3. doi: 10.1097/00004850-199511000-00009.
A case of acute akathisia induced by lithium treatment is described. Since lithium administration leads to activation of serotonergic neurotransmission, the 5-HT2A/2C and 5-HT3 antagonist mianserin was added as a possible anti-akathitic agent. Mianserin treatment (15 mg/day at 21.00 h) resulted in amelioration of the lithium-induced akathisia.
本文描述了一例由锂盐治疗引起的急性静坐不能病例。由于锂盐给药会导致血清素能神经传递的激活，因此添加了5-HT2A/2C和5-HT3拮抗剂米安色林作为一种可能的抗静坐不能药物。米安色林治疗（每天15毫克，于21:00服用）使锂盐引起的静坐不能症状得到改善。
