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三叉神经痛患者经皮甘油神经根切断术前、后的瞬目反射——28例患者的前瞻性研究

The blink reflex before and after percutaneous glycerol rhizotomy in patients with trigeminal neuralgia--a prospective study of 28 patients.

作者信息

Kumar R, Mahapatra A K, Dash H H

机构信息

Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi.

出版信息

Acta Neurochir (Wien). 1995;137(1-2):85-8. doi: 10.1007/BF02188787.

Abstract

The blink reflex was prospectively studied in 28 patients with trigeminal neuralgia, prior-to and following percutaneous glycerol rhizotomy to the Gasserian ganglion. Fifteen patients (54%) had varying degrees of sensory loss in the trigeminal nerve distribution already before glycerol injection. Three more patients developed sensory loss following glycerol injection. Thus following glycerol injection 18 patients had graded sensory loss. Pre-injection the blink reflex showed abnormal R1 wave in 57% patients, while direct and consensual R2 waves were abnormal in 43% and 48%, respectively. Post-injection R1 wave was abnormal in 64% patients. Direct R2 waves were abnormal in 33% patients. Thus clinical findings of sensory loss correlated well with pre-and post-injection blink reflex abnormality. Postoperatively R1 and ipsilateral R2 latencies from the side of the injection deteriorated and consensual R2 latency improved, thus, signifying better function on the contralateral side following relief of pain by glycerol rhizotomy.

摘要

对28例三叉神经痛患者在经皮向半月神经节注射甘油之前和之后进行了前瞻性的瞬目反射研究。15例患者(54%)在甘油注射前三叉神经分布区域就已经有不同程度的感觉丧失。另外3例患者在甘油注射后出现感觉丧失。因此,甘油注射后18例患者有不同程度的感觉丧失。注射前,57%的患者瞬目反射R1波异常,而直接R2波和双侧R2波异常分别为43%和48%。注射后,64%的患者R1波异常,33%的患者直接R2波异常。因此,感觉丧失的临床发现与注射前后瞬目反射异常密切相关。术后,注射侧的R1和同侧R2潜伏期延长,双侧R2潜伏期缩短,这表明甘油切断术缓解疼痛后对侧功能改善。

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