Tsuzuku T, Vitte E, Sémont A, Berthoz A
Collège de France, CNRS Laboratoire de Physiologie de la Perception et de l'Action, Paris, France.
Acta Otolaryngol Suppl. 1995;520 Pt 2:419-22. doi: 10.3109/00016489509125287.
Eye movements were recorded in patients with unilateral and bilateral vestibular lesions after upward and downward optokinetic (OK) stimulation before and following 6 weeks' repeated exposure to OK stimulation. In control subjects there was no asymmetry between upward and downward slow-phase velocity (SPV). Before training, less subjects showed that upward and downward SPV was significantly lower than that of controls. There was no asymmetry between upward and downward SPV. After training, in unilateral cases, the values of both upward and downward SPV recovered to the control range. In bilateral cases, the downward SPV values returned to the control range, whereas the values of upward SPV exceeded the control range. The frequencies of both upward and downward OKN in controls were about 3.0 Hz. In unilateral and bilateral cases, before and after training, the OKN frequencies approximated 3.0 Hz, showing no significant differences. The recovery of the SPV in unilateral and bilateral cases after training suggests that OK stimulation acts to stabilize the body and consequently to provoke pronounced OKN, due to eye-head-body co-ordination. The asymmetry of SPV after training in bilateral cases might be a result of the lack of otolith function.
在单侧和双侧前庭病变患者中，于向上和向下视动（OK）刺激前后记录眼球运动，刺激前及重复接受OK刺激6周后进行。在对照受试者中，向上和向下慢相速度（SPV）之间无不对称性。训练前，较少受试者表现出向上和向下SPV显著低于对照组。向上和向下SPV之间无不对称性。训练后，在单侧病例中，向上和向下SPV值均恢复至对照范围。在双侧病例中，向下SPV值恢复至对照范围，而向上SPV值超过对照范围。对照组中向上和向下视动性眼震（OKN）的频率均约为3.0 Hz。在单侧和双侧病例中，训练前后OKN频率接近3.0 Hz，无显著差异。训练后单侧和双侧病例中SPV的恢复表明，由于眼-头-身体协调，OK刺激起到稳定身体的作用，从而引发明显的OKN。双侧病例训练后SPV的不对称性可能是耳石功能缺失的结果。
