Mueller R K, Grosse J, Lang R, Thieme D
Institute of Doping Analysis and Sports Biochemistry, Kreischa, Germany.
J Chromatogr B Biomed Appl. 1995 Dec 1;674(1):1-11. doi: 10.1016/0378-4347(95)00290-8.
The principal definition of doping, the groups of banned compounds and the basic analytical problems and strategy of doping analysis are outlined, and the position of chromatography in doping analysis is explained. Examples of the application of GC-MS, especially high-resolution MS. and of LC-thermospray MS to doping problems are given. A practical case is presented briefly, showing the post-analytical problem of evaluating even unequivocal results.
概述了兴奋剂的主要定义、禁用化合物类别、兴奋剂分析的基本分析问题及策略,并解释了色谱法在兴奋剂分析中的地位。给出了气相色谱-质谱联用(尤其是高分辨率质谱)以及液相色谱-热喷雾质谱在兴奋剂问题分析中的应用实例。简要介绍了一个实际案例,展示了即使对于明确的结果进行评估时的分析后问题。