原子分辨率下的蛋白质。

Proteins at atomic resolution.

作者信息

Dauter Z, Lamzin V S, Wilson K S

机构信息

European Molecular Biology Laboratory, Hamburg, Germany.

出版信息

Curr Opin Struct Biol. 1995 Dec;5(6):784-90. doi: 10.1016/0959-440x(95)80011-5.

DOI:10.1016/0959-440x(95)80011-5

PMID:8749366

Abstract

Experimental advances in data collection, including bright sources, cryogenic cooling and two-dimensional detectors, have made it tractable to record data to beyond 1.2 A for several proteins, yielding high-accuracy models and fine details of structure. For small metalloproteins, atomic-resolution data have enabled ab initio solution of the phase problem.

摘要

数据收集方面的实验进展，包括强光源、低温冷却和二维探测器，使得记录几种蛋白质分辨率超过1.2埃的数据变得可行，从而得到高精度模型和精细的结构细节。对于小型金属蛋白，原子分辨率数据已能够从头解决相位问题。