Sing R F, Reilly P M, Rotondo M F, Lynch M J, McCans J P, Schwab C W
Division of Trauma/Surgical Critical Care, University of Pennsylvania Medical Center, Philadelphia, USA.
Acad Emerg Med. 1996 Jan;3(1):41-5. doi: 10.1111/j.1553-2712.1996.tb03301.x.
To determine the effectiveness and morbidity of out-of-hospital rapid-sequence induction (RSI) for endotracheal intubation (ETI) in the pediatric population.
The medical records were retrospectively reviewed for a consecutive series of pediatric patients undergoing out-of-hospital RSI by flight paramedics from July 1990 through July 1994. Patient demographics, pharmacologic agents, ED arterial blood gas data, pulmonary complications, and RSI-related complications were abstracted.
Forty patients (31 injured, 9 medical) with a mean age of 8.1 years (range 0.5-17 years) underwent out-of-hospital RSI. Indications for intubation included hyperventilation (n = 20), combativeness (n = 16), apnea (n = 5), and unknown (n = 5). Intubation mishaps occurred in 13 patients (33%); these included multiple attempts (n = 9), aspiration (n = 8), and esophageal intubation (n = 1). The success rate of ETI was 97.5% (one failed attempt). Hemodynamic side effects occurred in three patients (8%); all three had bradycardia, with one developing hypotension. Bradycardia was associated with failure to pretreat with atropine (p < 0.05). Sixteen pulmonary complications, seven pneumonia (18%) and nine atelectasis (22.5%), occurred in 13 patients within the first ten hospital days. Intubation mishaps were not associated with pulmonary complications. There were six deaths, none associated with RSI.
确定院外快速顺序诱导插管(RSI)用于儿科患者气管插管(ETI)的有效性及发病率。
回顾性分析1990年7月至1994年7月间飞行医护人员对一系列连续的儿科患者进行院外RSI的病历。提取患者人口统计学资料、药物、急诊动脉血气数据、肺部并发症及与RSI相关的并发症。
40例患者(31例受伤,9例内科疾病)平均年龄8.1岁(范围0.5 - 17岁)接受了院外RSI。插管指征包括通气过度(n = 20)、好斗(n = 16)、呼吸暂停(n = 5)及原因不明(n = 5)。13例患者(33%)发生插管失误;包括多次尝试(n = 9)、误吸(n = 8)及食管插管(n = 1)。ETI成功率为97.5%(1次尝试失败)。3例患者(8%)出现血流动力学副作用;3例均有心动过缓,1例出现低血压。心动过缓与未用阿托品预处理有关(p < 0.05)。13例患者在入院后的前10天内出现16例肺部并发症,7例肺炎(18%)和9例肺不张(22.5%)。插管失误与肺部并发症无关。有6例死亡,均与RSI无关。
1)快速顺序诱导是获得危重症儿科患者气道控制的有效方法。2)插管失误不影响肺部并发症发生率。3)儿科患者RSI期间未用阿托品与心动过缓有关。