Sahin-Akyar G, Sumer H
Department of Radiology, University of Ankara, Faculty of Medicine, Ibn-i Sina Hospital, Turkey.
Invest Radiol. 1996 Feb;31(2):72-9. doi: 10.1097/00004424-199602000-00002.
The purpose of this study was to evaluate the usefulness of color Doppler and spectral analysis of specific tumor vessels in the differentiation of benign from malignant breast masses.
Forty-eight patients with solid breast masses were evaluated with color Doppler ultrasound prospectively. When tumor vessels were visualized, spectral analysis was performed and peak systolic and end diastolic Doppler frequency shifts were recorded. Histology was obtained in all but two cases.
In 28 out of 29 malignant lesions tumor vessels were visualized. Thirteen of 19 benign lesions showed no demonstrable flow. The peak systolic Doppler frequency shifts recorded over the vessels of the malignant breast masses were significantly higher than those of the benign breast masses (P < 0.01).
In our preliminary series, spectral Doppler analysis of tumor vessels shows promise in differentiating benign from malignant breast masses.
本研究的目的是评估彩色多普勒及特定肿瘤血管的频谱分析在鉴别乳腺良恶性肿块中的作用。
对48例乳腺实性肿块患者进行前瞻性彩色多普勒超声评估。当观察到肿瘤血管时，进行频谱分析并记录收缩期峰值和舒张末期多普勒频移。除2例患者外，其余均获得了组织学检查结果。
29个恶性病变中有28个观察到肿瘤血管。19个良性病变中有13个未显示出可检测到的血流。乳腺恶性肿块血管上记录的收缩期峰值多普勒频移显著高于良性乳腺肿块（P < 0.01）。
在我们的初步研究中，肿瘤血管的频谱多普勒分析在鉴别乳腺良恶性肿块方面显示出前景。
