Barten S, Proesmans W
Renal Unit, University Hospital Gasthuisberg, Leuven, Belgium.
Eur J Pediatr. 1996 Jan;155(1):49-52. doi: 10.1007/BF02115627.
The clinical, histological and genetic features of Alport syndrome are presented and illustrated by our experience with 21 paediatric patients seen over the last 22 years. From the 15 boys, 7 went into end-stage renal failure before the age of 20 years. In the 6 girls, the symptomatology was limited to permanent haematuria and mild proteinuria.
Alport syndrome should be included in the differential diagnosis of permanent haematuria even in the absence of any suggestive familial antecedent.
通过我们在过去22年中诊治的21例儿科患者的经验，介绍并说明了奥尔波特综合征的临床、组织学和遗传学特征。在15名男孩中，7名在20岁前进入终末期肾衰竭。在6名女孩中，症状仅限于持续性血尿和轻度蛋白尿。
即使没有任何提示性的家族史，奥尔波特综合征也应列入持续性血尿的鉴别诊断中。
