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烟曲霉性巩膜炎

Aspergillus fumigatus scleritis.

作者信息

Rodriguez-Ares M T, De Rojas Silva M V, Pereiro M, Fente Sampayo B, Gallegos Chamas G, S-Salorio M

机构信息

Department of Ophthalmology and Dermatology, University of Santiago de Compostela, Spain.

出版信息

Acta Ophthalmol Scand. 1995 Oct;73(5):467-9. doi: 10.1111/j.1600-0420.1995.tb00312.x.

Abstract

We report a case of scleritis caused by Aspergillus fumigatus. The infection was successfully treated with antifungal drugs, cryotherapy and dura mater grafting. A 67-year-old man developed a scleral ulcer 2 months after suffering a trauma in his right eye caused by the branch of a tree. Diagnosis was made after biopsy of a scleral nodule. Scrapings showed hyphal fragments and cultures were positive for Aspergillus fumigatus. Although therapy with oral fluconazol and topical amphotericin B was begun, the scleritis continued to worsen, so cryotherapy and dura mater grafting were performed. The patient showed no signs of infection for 8 months after discontinuation of antifungal drugs.

摘要

我们报告一例由烟曲霉引起的巩膜炎病例。该感染通过抗真菌药物、冷冻疗法和硬脑膜移植成功治愈。一名67岁男性在右眼被树枝划伤2个月后出现巩膜溃疡。经巩膜结节活检后确诊。刮片显示有菌丝片段,培养结果显示烟曲霉呈阳性。尽管开始使用口服氟康唑和局部两性霉素B进行治疗,但巩膜炎仍继续恶化,因此进行了冷冻疗法和硬脑膜移植。停用抗真菌药物8个月后,患者未出现感染迹象。

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