Colafranceschi M, Bettocchi S, Mencaglia L, van Herendael B J
Institute of Pathology, University of Florence, Florence, Italy.
Gynecol Oncol. 1996 Aug;62(2):298-300. doi: 10.1006/gyno.1996.0230.
Endometrial ablation or resection using hysteroscopy appears to be an effective treatment for menorrhagia resistant to medical therapy. Three patients with endometrial adenocarcinoma missed in the preoperative hysteroscopic and histological assessment and subjected to endometrial resection were collected in a multicenter study. One case was an early adenocarcinoma in the background of late proliferative endometrium in a 39-year-old woman. In the other two patients, ages 51 and 68, the adenocarcinoma developed in a polyp in a background of simple hyperplasia. Since hysteroscopy with endometrial biopsy might not be able to exclude the presence of an early intrauterine cancer, appropriate selection and accurate evaluation of patients are imperative before ablative surgery. Endometrial resection is preferred over endometrial laser ablation since it provides additional tissue for histologic examination.
使用宫腔镜进行子宫内膜消融或切除术似乎是治疗药物治疗无效的月经过多的有效方法。在一项多中心研究中，收集了3例术前宫腔镜检查和组织学评估漏诊且接受了子宫内膜切除术的子宫内膜腺癌患者。1例为39岁女性，在增殖晚期子宫内膜背景下的早期腺癌。另外2例患者年龄分别为51岁和68岁，腺癌发生于单纯增生背景下的息肉中。由于宫腔镜检查及子宫内膜活检可能无法排除早期子宫内癌的存在，因此在进行消融手术前，必须对患者进行适当的选择和准确的评估。子宫内膜切除术优于子宫内膜激光消融术，因为它能提供额外的组织用于组织学检查。
