Gollub M J, Gruen D R, Dershaw D D
Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
AJR Am J Roentgenol. 1996 Sep;167(3):617-20. doi: 10.2214/ajr.167.3.8751663.
The purpose of this report is to determine CT imaging findings in patients with Merkel cell carcinoma.
Fifty-three CT scans in 12 patients with biopsy-proven Merkel cell carcinoma were retrospectively reviewed with regard to size, location, and attenuation of primary skin lesions and visceral and lymph node metastases. Findings that were present in 12 patients form the basis of this report.
Primary skin lesions were manifested on CT scans in four patients as cutaneous nodules that were hyper- or isodense in relation to muscle. Sites of metastases included regional lymph nodes (n = 6), distant lymph nodes (n = 11), the liver (n = 3), and subcutaneous fat (n = 4). We also found metastases in the mediastinum, the peritoneum, the adrenal gland, and the lung. Usually nodal and subcutaneous metastases were slightly hyperdense. Subcutaneous linear stranding was associated with the lesions.
CT is useful in the staging of Merkel cell carcinoma.
本报告旨在确定默克尔细胞癌患者的CT影像表现。
回顾性分析12例经活检证实为默克尔细胞癌患者的53次CT扫描结果，观察原发皮肤病变以及内脏和淋巴结转移灶的大小、位置和密度。本报告基于12例患者的检查结果。
4例患者的原发皮肤病变在CT扫描上表现为相对于肌肉呈高密度或等密度的皮肤结节。转移部位包括区域淋巴结（n = 6）、远处淋巴结（n = 11）、肝脏（n = 3）和皮下脂肪（n = 4）。我们还发现纵隔、腹膜、肾上腺和肺部有转移。通常，淋巴结和皮下转移灶略呈高密度。皮下条索状影与病变相关。
CT对默克尔细胞癌的分期有帮助。
