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[小细胞肺癌的化疗]

[Chemotherapy of small cell lung cancer].

作者信息

Komiya T, Takada M

机构信息

Second Dept. of Internal Medicine, Osaka Prefectural Habikino Hospital, Japan.

出版信息

Gan To Kagaku Ryoho. 1996 Aug;23(9):1116-23.

PMID:8751797
Abstract

Chemotherapy of small cell lung cancer is reviewed. Combination chemotherapy with cisplatin/etoposide (PE) or CAV (cyclophosphamide, adriamycin and vincristine) alternating with PE was established as standard regimens. Dose intensive chemotherapy, such as weekly regimens or using G-CSF, is being investigated. In patients with limited disease (LD), combined modality treatment is proven to produce favorable results, but the best sequence or fractionation of thoracic radiotherapy is unknown. More progress in the treatment of small cell lung cancer is expected.

摘要

本文综述了小细胞肺癌的化疗。顺铂/依托泊苷(PE)或环磷酰胺、阿霉素和长春新碱(CAV)与PE交替使用的联合化疗已成为标准方案。正在研究剂量密集化疗,如每周方案或使用粒细胞集落刺激因子(G-CSF)。在局限性疾病(LD)患者中,综合治疗已被证明能产生良好效果,但胸部放疗的最佳顺序或分割方式尚不清楚。预计小细胞肺癌的治疗将取得更多进展。

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