Grubb D K, Kjos S L, Paul R H
Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, USA.
Obstet Gynecol. 1996 Sep;88(3):351-5. doi: 10.1016/0029-7844(96)00197-4.
To determine if avoiding the augmentation of ineffective contractions in women with unknown uterine scars would decrease the risk of cesarean for protraction disorders, compared with awaiting the onset of spontaneous labor.
Term gravidas with one or two unknown uterine scars in early labor were randomized to nonintervention (N = 101) and intervention (N = 96) groups. Nonintervention subjects were discharged if cervical change did not occur within 4 hours. Intervention subjects were admitted. Contractions that persisted for 4 hours without cervical change were augmented with oxytocin.
Intervention subjects received oxytocin significantly more often (82 versus 55%, P < .001) and had a statistically significantly higher rate of uterine scar separation (5 versus 0%, P = .03). There was no difference between the two groups in length of active labor (4.0 versus 4.25 hours) or incidence of cesarean delivery (16 versus 17%).
The augmentation of ineffective contractions during latent labor in gravidas with an unknown uterine scar does not increase the rate of cesarean delivery, but it is significantly more likely to result in uterine scar separations.
与等待自然临产相比,确定避免增强子宫瘢痕情况不明的女性无效宫缩是否会降低因产程延长而行剖宫产的风险。
将产程早期有一或两条子宫瘢痕情况不明的足月孕妇随机分为非干预组(N = 101)和干预组(N = 96)。若4小时内宫颈无变化,非干预组受试者出院。干预组受试者入院。持续4小时且宫颈无变化的宫缩用缩宫素增强。
干预组受试者使用缩宫素的频率显著更高(82%对55%,P <.001),子宫瘢痕分离率在统计学上显著更高(5%对0%,P =.03)。两组在活跃期产程时长(4.0小时对4.25小时)或剖宫产发生率(16%对17%)上无差异。
子宫瘢痕情况不明的孕妇在潜伏期增强无效宫缩不会增加剖宫产率,但显著更易导致子宫瘢痕分离。