肿瘤标志物与经阴道超声检查在卵巢巧克力囊肿诊断中的应用
Tumor markers and transvaginal ultrasonography in the diagnosis of endometrioma.
作者信息
Guerriero S, Ajossa S, Paoletti A M, Mais V, Angiolucci M, Melis G B
机构信息
Department of Obstetrics and Gynecology, Univeŗsity of Cagliari, Italy.
出版信息
Obstet Gynecol. 1996 Sep;88(3):403-7. doi: 10.1016/0029-7844(96)00204-9.
OBJECTIVE
To evaluate the accuracy of CA 19.9 plasma levels (with or without CA 125 levels) combined with transvaginal ultrasonography in the differential diagnosis of endometrioma.
METHODS
One hundred eighteen consecutive premenopausal nonpregnant women had laparoscopy or laparotomy between November 1994 and November 1995 because of the presence of a persistent adnexal mass. They underwent transvaginal ultrasonography and measurement of CA 19.9 and CA 125 plasma levels within 2 days before surgery. The ultrasonographic impression and the tumor marker values were compared with the histopathologic diagnosis. The overall agreement between the test result and the actual outcome was calculated using the kappa statistic.
RESULTS
Transvaginal ultrasonography had a strong agreement between test result and surgery (kappa value 0.84), whereas the combined methods were associated with a lower kappa value (range 0.24-0.80).
CONCLUSION
Transvaginal ultrasonography used alone is the most cost-effective method in the preoperative differential diagnosis of endometrioma.
目的
评估CA 19.9血浆水平（无论有无CA 125水平）联合经阴道超声检查在子宫内膜异位囊肿鉴别诊断中的准确性。
方法
1994年11月至1995年11月期间，118例连续的绝经前未孕妇女因存在持续性附件包块接受了腹腔镜检查或剖腹手术。她们在手术前2天内接受了经阴道超声检查以及CA 19.9和CA 125血浆水平测定。将超声检查结果和肿瘤标志物值与组织病理学诊断进行比较。使用kappa统计量计算检查结果与实际结果之间的总体一致性。
结果
经阴道超声检查的检查结果与手术结果之间有很强的一致性（kappa值为0.84），而联合检查方法的kappa值较低（范围为0.24 - 0.80）。
结论
单独使用经阴道超声检查是子宫内膜异位囊肿术前鉴别诊断中最具成本效益的方法。
Zotero 插件