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[预测性基因诊断的伦理问题]

[Ethical aspect of predictive gene diagnosis].

作者信息

Furukawa T

机构信息

Department of Allied Health Sciences, Faculty of Medicine, Tokyo Medical and Dental University.

出版信息

Rinsho Shinkeigaku. 1995 Dec;35(12):1535-6.

PMID:8752455
Abstract

Progress of gene diagnosis has made it possible to predict whether a man develops any particular disease. The typical case is Huntington's disease. However, predictive gene diagnosis profits anything? Not a few persons at risk of the disease do not want to receive predictive diagnosis. Some investigators assert that if informed consent is available, there is no problem to do the test. However, to force the client to decide whether to receive or not the diagnosis is a great cruelty for them. Investigators must recognize their pitiable states. Predictive gene diagnosis offers an important problem whether precognition in general is really worthwhile. Cicero told us "It is no use to foresee the future, if there is no profit", and today this sentence is still alive. Today's medicine has inclined to neglect patients themselves. Men, who have paid the highest respect for reason and almighty sciences, must remember the following philosophical prose of Alexander Pope: "Know then thyself, presume not God to scan; The proper study of Mankind is Man."

摘要

基因诊断的进展使得预测一个人是否会患上某种特定疾病成为可能。典型的例子是亨廷顿舞蹈症。然而,预测性基因诊断有什么益处呢?不少有患该病风险的人并不想接受预测性诊断。一些研究者断言,如果能获得知情同意,进行检测就没有问题。然而,强迫客户决定是否接受诊断对他们来说是极大的残忍。研究者必须认识到他们可怜的处境。预测性基因诊断提出了一个重要问题,即一般而言的预知是否真的有价值。西塞罗告诉我们“如果没有益处,预知未来毫无用处”,如今这句话仍然适用。当今的医学倾向于忽视患者自身。那些极度尊崇理性和万能科学的人,必须记住亚历山大·蒲柏的以下哲学散文:“认识你自己,勿擅自揣度上帝;人类真正的研究对象是人。”

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