Mitsui K, Honda N, Kamijou A, Hiraiwa S, Yamada Y, Fukatsu H, Yoshikawa K
Department of Urology, Aichi Medical University.
Hinyokika Kiyo. 1996 May;42(5):369-72.
We experienced a case of renal oncocytoma, in a 46-year-old woman. At a health examination, ultrasonography revealed a right renal tumor, and she was admitted to our hospital for evaluation. From the ultrasonogram, computerized tomography (CT) and angiography, we suspected a renal oncocytoma, but renal cell carcinoma was not completely ruled out. Since the location of the tumor seemed suitable for a local resection, we scheduled a surgical enucleation, but we intended to switch to a radical nephrectomy if examination of a frozen-section suggested renal cancer. Because the frozen findings were suggestive of an oncocytoma without malignancy, the surgical enucleation procedure was completed as scheduled. Pathological findings of the resected specimens were characterized by granular eosinophilic cytoplasm, and rounded nuclei without nuclear pleomorphism or mitotic figures. Electron microscopic studies revealed an increased number of mitochondria. The patient was accordingly diagnosed as having renal oncocytoma. We also reviewed the literature to elaborate procedures for a preoperative diagnosis and therapy for renal oncocytoma.
我们遇到一例46岁女性肾嗜酸细胞瘤患者。在一次健康检查中，超声检查发现右肾有肿瘤，她因此入院接受评估。通过超声检查、计算机断层扫描（CT）和血管造影，我们怀疑是肾嗜酸细胞瘤，但未完全排除肾细胞癌。由于肿瘤位置似乎适合局部切除，我们安排了手术摘除，但如果冰冻切片检查提示为肾癌，我们打算改为根治性肾切除术。因为冰冻切片结果提示为无恶性特征的嗜酸细胞瘤，所以手术摘除按计划完成。切除标本的病理结果表现为颗粒状嗜酸性细胞质，细胞核圆形，无核异形或有丝分裂象。电子显微镜研究显示线粒体数量增加。该患者因此被诊断为肾嗜酸细胞瘤。我们还查阅了文献，以详细阐述肾嗜酸细胞瘤的术前诊断和治疗程序。
