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经导管动脉栓塞治疗肾血管平滑肌脂肪瘤的长期疗效

[Long-term effect of transcatheter arterial embolization therapy for renal angiomyolipoma].

作者信息

Sasaki M, Kawabata M, Asaji A, Takakuwa H, Ohta H, Kobayashi K, Matsui O, Kato Y

机构信息

First Department of Internal Medicine, School of Medicine, Kanazawa University, Japan.

出版信息

Nihon Jinzo Gakkai Shi. 1996 Jun;38(6):273-7.

PMID:8752970
Abstract

We report a case of a 21-year-old man with a right renal angiomyolipoma who has been observed for 20 months after successful treatment with selective transcatheter arterial embolization (TAE). In May 1993, he was transferred to our hospital for the treatment of an abdominal mass. Examination revealed a solid and fat-containing right renal tumor on computed tomography (CT) and magnetic resonance imaging (MRI), hypervascular staining with multiple peripheral microaneurysms on renal angiogram, indicating an angiomyolipoma (AML). He did not have any signs of tuberous sclerosis. Because he complained of abdominal pain and the tumor was 9 cm in diameter, TAE of the tumor using polyvinyl alcohol foam was performed to prevent life-threatening hemorrhage. Renal angiogram after TAE demonstrated a complete shut-down of blood supply to the tumor and CT scan, 6 and 20 months after TAE, demonstrated a decrease in size to 4.5 cm in diameter, showing a favorable long-term effect of treatment. He has been symptom-free for 20 months. TAE appears to be a safe and effective treatment for AML, preventing tumor growth and thus possibly hemorrhage or rupture of the tumor over the long -term.

摘要

我们报告一例21岁男性右肾血管平滑肌脂肪瘤患者,在选择性经导管动脉栓塞术(TAE)成功治疗后已观察20个月。1993年5月,他因腹部肿块被转诊至我院治疗。检查发现,计算机断层扫描(CT)和磁共振成像(MRI)显示右肾有一个含实性成分和脂肪的肿瘤,肾血管造影显示有高血管染色及多个外周微动脉瘤,提示为血管平滑肌脂肪瘤(AML)。他没有结节性硬化症的任何体征。由于他主诉腹痛且肿瘤直径为9厘米,遂采用聚乙烯醇泡沫对肿瘤进行TAE,以防止危及生命的出血。TAE术后肾血管造影显示肿瘤供血完全中断,TAE术后6个月和20个月的CT扫描显示肿瘤直径缩小至4.5厘米,显示出良好的长期治疗效果。他已20个月无症状。TAE似乎是一种治疗AML的安全有效的方法,可防止肿瘤生长,从而可能长期预防肿瘤出血或破裂。

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