Anders N, Pham D T, Linke C, Wollensak J
Augenklinik, Virchow-Klinikum der Humboldt-Universität zu Berlin.
Ophthalmologe. 1996 Jun;93(3):279-83.
The first experiments for surgical correction of higher astigmatism were reported more than 100 years ago. A lot of different procedures were strongly recommended at the beginning but then abandoned later on because they could not fulfill the expectations regarding the postoperative results and the complications. On the other hand, lamellar preparation of the cataract incision has been considered a major advance in ophthalmology. The main advantage of this incision is that it yields stable postoperative refraction as well as high mechanical stability very early (postoperatively). These findings prompted us to combine the advantages mentioned above with those of the arcuate transverse incision. In this report we present our experimental and clinical results with arcuate lamellar keratotomy.
Experiments were carried out on 22 cadaver bulbi. The optical zones ranged from 6 to 8 mm and the length of the arcuate incisions was between 2 and 7 mm. The clinical data presented here were obtained from 20 patients with a 4-week follow-up. These 20 patients had undergone cataract surgery previously with an induced astigmatism ranging from 2.5 to 5 D. Patients were treated with an optical zone of 7 mm or 8 mm. The length of the arcuate incision was 3 mm. All incisions were paired.
Our experiments (cadaver bulbi) showed an approximately linear decrease of the effect with increasing width of the optical zone and increasing are length. Our clinical results demonstrate that the astigmatism induced by our procedure (including potential overcorrection) was 3.41 +/- 1.33 D on the the first day postoperatively. All astigmatism was measured with the Zeiss keratometer. After 1 and 4 weeks the results were 3.98 +/- 1.35 and 3.71 +/- 1.29 D, respectively. The induced astigmatism also depended on the width of the optical zone. In the group with a 7 mm optical zone the induced astigmatism was 4.5 +/- 1.56 D after 4 weeks. This effect was remarkably higher than in the 8 mm group with an average of 3.35 +/- 0.94 D of induced astigmatism. There were no significant differences between visual acuity under glare conditions and the number of endothelial cells preoperatively and at 4 weeks follow-up, nor were there variations in refraction, depending on the time of day.
Due to the relatively high standard deviation of the induced astigmatism we must keep trying to make the results of our procedure more predictable.
100多年前就有了关于手术矫正高度散光的首次实验报告。起初强烈推荐了许多不同的手术方法,但后来都被放弃了,因为它们无法达到对术后效果和并发症的预期。另一方面,白内障切口的板层制备被认为是眼科领域的一项重大进展。这种切口的主要优点是术后能很早获得稳定的屈光状态以及高机械稳定性。这些发现促使我们将上述优点与弧形横向切口的优点相结合。在本报告中,我们展示了弧形板层角膜切开术的实验和临床结果。
在22只尸体眼球上进行实验。光学区范围为6至8毫米,弧形切口长度在2至7毫米之间。此处呈现的临床数据来自20例患者,随访4周。这20例患者此前接受过白内障手术,诱导散光范围为2.5至5 D。患者接受7毫米或8毫米光学区的治疗。弧形切口长度为3毫米。所有切口均为成对。
我们的实验(尸体眼球)表明,随着光学区宽度增加和弧长增加,效果大致呈线性下降。我们的临床结果表明,术后第一天我们手术诱导的散光(包括潜在的过矫正)为3.41±1.33 D。所有散光均用蔡司角膜曲率计测量。1周和4周后结果分别为3.98±1.35和3.71±1.29 D。诱导散光还取决于光学区宽度。在光学区为7毫米的组中,4周后诱导散光为4.5±1.56 D。这种效果明显高于8毫米组,8毫米组诱导散光平均为3.35±0.94 D。在眩光条件下的视力、术前和随访4周时的内皮细胞数量之间没有显著差异,屈光也没有因一天中的时间而变化。
由于诱导散光的标准差相对较高,我们必须不断努力使我们手术的结果更具可预测性。