Tseĭtlin A M, Lubnin A Iu, Baranov O A, Luk'ianov V I
Anesteziol Reanimatol. 1996 Mar-Apr(2):46-9.
Pressor reaction to laryngoscopy and intubation of the trachea was studied in 32 patients with neurosurgical diseases of the brain (supratentorial tumors and arterial aneurysms) under conditions of induction anesthesia with propofol (diprivan) in the mean dose of 2.85 mg/kg. Diprivan alone did not block the development of pronounced pressor reaction to intubation. Combination of diprivan in the same dose with dipidolor (0.4 mg/kg) ensured complete blocking of the pressor reaction in neurosurgical patients. Combination of diprivan and fentanyl (2.85 mg/kg) blocked the development of a pressor reaction not so effectively and not in all the examinees.
在32例患有脑部神经外科疾病（幕上肿瘤和动脉瘤）的患者中，使用平均剂量为2.85mg/kg的丙泊酚（得普利麻）进行诱导麻醉，研究了喉镜检查和气管插管时的升压反应。单独使用得普利麻并不能阻止插管时明显升压反应的发生。相同剂量的得普利麻与双氯芬酸（0.4mg/kg）联合使用可确保神经外科患者的升压反应完全被阻断。得普利麻与芬太尼（2.85mg/kg）联合使用对升压反应的阻断效果不佳，且并非对所有受试者都有效。
