Salinas Casado J, Aristizabal Agudelo J M, Virseda Chamorro M, Esteban Fuertes M, Resel Estévez L
Servicio de Urología, Hospital Universitario San Carlos, Universidad Complutense, Madrid, España.
Arch Esp Urol. 1996 May;49(4):405-12.
To determine the utility of the DURR (dynamic urethral resistance factor) in the evaluation of prostatism.
248 patients with prostatism were evaluated by the detrusor pressure-flow rate test, perineal and periurethral EMG and voiding videocystography. The Audit software program was utilized to process the data from the pressure-flow studies to obtain the parameters for urethral resistance (PURR), bladder contractibility (Wmax) and DURR.
The presence of DURR correlated significantly with abdominal voiding pressure and voluntary voiding, and constrictive obstruction, although a higher incidence of stenosis in patients with a positive DURR was not demonstrable on videocystography. No correlation was observed between EMG activity and a positive DURR.
A positive DURR indicates the effect of active urethral resistance changes on the voiding dynamics. These active changes can be caused by contraction of the periurethral muscles (EMG activity), although not all of the cases showing EMG activity have a positive DURR. Furthermore, in some DURR positive cases, the EMG is silent, indicating that the urethral smooth muscles are involved in the active changes of urethral resistance. The DURR data do not always coincide with the perineal EMG findings and therefore do not supplant each other.
确定动态尿道阻力因子（DURR）在前列腺增生评估中的作用。
对248例前列腺增生患者进行逼尿肌压力-流率测试、会阴及尿道周围肌电图（EMG）检查和排尿膀胱造影。利用Audit软件程序处理压力-流率研究数据，以获得尿道阻力（PURR）、膀胱收缩力（Wmax）和DURR参数。
DURR的存在与腹压排尿和自主排尿以及狭窄性梗阻显著相关，尽管在排尿膀胱造影中未证实DURR阳性患者的狭窄发生率更高。未观察到肌电图活动与DURR阳性之间存在相关性。
DURR阳性表明尿道阻力的主动变化对排尿动力学有影响。这些主动变化可能由尿道周围肌肉收缩（肌电图活动）引起，尽管并非所有显示肌电图活动的病例DURR均为阳性。此外，在一些DURR阳性病例中，肌电图无活动，表明尿道平滑肌参与了尿道阻力的主动变化。DURR数据并不总是与会阴肌电图结果一致，因此二者不能相互替代。
