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[化脓性肝脓肿。35例描述性研究]

[Pyogenic liver abscess. A descriptive study of 35 cases].

作者信息

Ramos A, Gazapo T, Murillas J, Martín H, Mendaza P, Cuervas-Mons V

机构信息

Servicios de Medicina Interna III, Clinica Puerta de Hierro. Madrid.

出版信息

Gastroenterol Hepatol. 1996 Jun-Jul;19(6):292-6.

PMID:8754415
Abstract

Thirty-five patients with pyogenic hepatic abscess (PHA) attended over 13 years in a general hospital were studied. The aim of the study was to know the usefulness of the performance of opaque enema in patients with cryptogenic PHA and the prognosis of the patients treated with only antibiotics. The most frequent clinical and analytical manifestations were fever and leukocytosis. Other less frequent findings were abdominal pain, hepatomegaly and elevated alkaline phosphatase and aspartate aminotransferase levels. One third of the patients presented radiologic alterations at the base of the right hemithorax. Colon studies in the patients with cryptogenic PHA performed to discard another origin of the abscess demonstrated very low profitability. Abdominal echography showed adequate sensitivity (0.85) in the diagnosis of PHA and allowed percutaneous drainage to be performed in most of the cases. The patients who were treated with only antibiotics presented a significantly worse prognosis than those treated with antibiotics and drainage (p = 0.03). Drainage of the PHA also allowed a decrease in the length of fever duration.

摘要

对一家综合医院13年期间收治的35例化脓性肝脓肿(PHA)患者进行了研究。本研究的目的是了解不明原因PHA患者进行不透明灌肠的作用以及仅接受抗生素治疗患者的预后情况。最常见的临床和分析表现为发热和白细胞增多。其他不太常见的表现为腹痛、肝肿大以及碱性磷酸酶和天冬氨酸转氨酶水平升高。三分之一的患者在右半胸底部出现放射学改变。对不明原因PHA患者进行结肠检查以排除脓肿的其他来源,结果显示其收益非常低。腹部超声检查对PHA诊断具有足够的敏感性(0.85),并且在大多数情况下可进行经皮引流。仅接受抗生素治疗的患者预后明显比接受抗生素和引流治疗的患者差(p = 0.03)。PHA引流还可缩短发热持续时间。

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