Osadchuk L V
Ontogenez. 1996 May-Jun;27(3):218-21.
We studied the cortisol level in blood serum and adrenal homogenates, as well as the in vitro production of cortisol in adrenals of silver fox embryos of both sexes in response to exogenous adrenocorticotropic hormone (ACTH) stimulation. The level of cortisol in blood serum did not show any significant changes during the embryo development, while its level in adrenals and production by adrenals in vitro increased progressively from Day 35 to Day 50 of prenatal life. We found that ACTH is capable of stimulating cortisol biosynthesis and production in vitro during all studied periods of embryogenesis.
我们研究了血清和肾上腺匀浆中的皮质醇水平，以及在体外，给予外源性促肾上腺皮质激素（ACTH）刺激后，雌雄银狐胚胎肾上腺中皮质醇的产生情况。在胚胎发育过程中，血清中的皮质醇水平未显示出任何显著变化，而其在肾上腺中的水平以及体外肾上腺的产生量在产前第35天至第50天逐渐增加。我们发现，在所有研究的胚胎发育阶段，ACTH都能够刺激体外皮质醇的生物合成和产生。
