Rudoĭ N M
Probl Tuberk. 1996(3):6-8.
The author describes the trends in frequency and nature of primary drug resistance throughout the last 3 decades. Favourable trends in 1980s changed for negative tendencies in 1990s which reflects deterioration of epidemiological situation by tuberculosis. Earlier establishment of drug resistance is possible basing on its direct determination in the conditions of massive bacterial discharge. In new-onset contacts antibioticogram should be primarily copied from that of contamination source, in recurrent disease antibioticogram should correspond to that obtained in the same patient at first test.
作者描述了过去三十年原发性耐药的频率和性质趋势。20世纪80年代的有利趋势在90年代转变为负面趋势，这反映了结核病流行病学状况的恶化。基于在大量细菌排出情况下的直接测定，有可能更早地确定耐药性。在新发病例接触者中，抗菌谱应首先照搬污染源的抗菌谱；在复发病例中，抗菌谱应与同一患者首次检测时获得的抗菌谱一致。
