Hsu C M, Huang L M, Kao Y F, Chin T W, Lee P I, Lin Y J, Chang L Y, Chiu H H, Lee C Y
Department of Pediatrics, Kuang-Tien General Hospital, Taichung, Taiwan, R.O.C.
Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1996 May-Jun;37(3):188-92.
The infection status of Legionella pneumophila in children and its role in pediatric community-acquired pneumonia were investigated. Because exposure to Legionella pneumophila may be highly variable and there has been no unanimously agreed-upon cut-off values in previous seroprevalence studies, 60 serum samples collected from infants aged 12 to 18 months were examined using immunofluorescence antibody test to determine the cut-off titer which represents past Legionella pneumophila infection. An IFA titer of greater than or equal to 32 was found to be suitable to represent past L. pneumophila infection. A seroepidemiological study of the prevalence of L. pneumophila in 180 children showed the prevalences in children aged 7 to 18 years to be between 28.4 and 35%. Fifty-three paired sera were tested to determine the role of Legionella pneumophila in pediatric, community-acquired, atypical pneumonia. The frequency of confirmed disease was 0% and of presumptive cases was 5.7%. Legionella pneumophila was not a common etiologic agent of pediatric pneumonia in Taiwan.
对儿童嗜肺军团菌的感染状况及其在儿童社区获得性肺炎中的作用进行了调查。由于接触嗜肺军团菌的情况可能差异很大，且以往血清流行率研究中尚无一致认可的临界值，因此对60份12至18个月龄婴儿的血清样本进行了免疫荧光抗体检测，以确定代表既往嗜肺军团菌感染的临界滴度。发现免疫荧光抗体（IFA）滴度大于或等于32适合代表既往嗜肺军团菌感染。一项对180名儿童嗜肺军团菌流行率的血清流行病学研究显示，7至18岁儿童的流行率在28.4%至35%之间。检测了53对血清，以确定嗜肺军团菌在儿童社区获得性非典型肺炎中的作用。确诊病例的发生率为0%，疑似病例的发生率为5.7%。在台湾，嗜肺军团菌不是儿童肺炎的常见病原体。
