Chuwa L M, Mwiruki G, Bilal M G, Mnubhi E K, Swai A B
Department of Clinical Chemistry, Faculty of Medicine, Muhimbili University College of Health Sciences.
East Afr Med J. 1996 May;73(5 Suppl):S21-3.
We measured the serum concentration of iron, zinc, copper and bromine in fifty malnourished children and twenty one healthy controls using energy dispersive X-ray fluorescence spectrometry. The mean ages for the study group and controls were 27.06 and 29 months respectively. The mean weights of the study and control groups were 7.32 and 12.05 +/- 3.07 kilogrammes respectively. The serum iron, zinc, copper and bromine mean levels in the study and control groups were Fe 14.6 (9.9) Zn 12.5 (11.9) Cu 16.5 (21.2) and Br 59.1 (63.0) micromoles per litre. Analysis of variance between the study group and controls showed a significant fall in copper levels even when adjusted for age sex and weight differences (F = 4.6586 p < 0.05). The wide distribution of concentrations of Iron noted in the malnourished children is probably due to haemolysis and rapid catabolism. The role of bromine in nutrition is yet to be established.
我们使用能量色散X射线荧光光谱法测量了50名营养不良儿童和21名健康对照者血清中铁、锌、铜和溴的浓度。研究组和对照组的平均年龄分别为27.06个月和29个月。研究组和对照组的平均体重分别为7.32千克和12.05±3.07千克。研究组和对照组血清中铁、锌、铜和溴的平均水平分别为每升14.6（9.9）微摩尔铁、12.5（11.9）微摩尔锌、16.5（21.2）微摩尔铜和59.1（63.0）微摩尔溴。研究组与对照组之间的方差分析显示，即使在对年龄、性别和体重差异进行校正后，铜水平仍显著下降（F = 4.6586，p < 0.05）。营养不良儿童中铁浓度的广泛分布可能是由于溶血和快速分解代谢。溴在营养中的作用尚未确定。
