Wood W C
Emory University School of Medicine, Atlanta, Georgia, USA.
Semin Oncol. 1996 Aug;23(4):446-52.
Mammographic screening has resulted in an epidemic of diagnoses of ductal carcinoma in situ (DCIS). These are often small, impalpable lesions that do not reflect the natural history of older series of DCIS found by palpation at a larger size. The behavior of DCIS is related to the histological grade and size of the tumor. Therapy is primarily surgical excision. Irradiation has been shown to halve the rate of recurrence after local excision. Therapeutic decisions involving the extent of surgical excision and the addition of irradiation are based on considerations of tumor size and grade and the patient's age.
乳腺钼靶筛查导致了导管原位癌（DCIS）诊断的流行。这些通常是微小的、触诊不到的病变，与过去通过触诊发现的较大尺寸的DCIS系列病例的自然病程不同。DCIS的行为与肿瘤的组织学分级和大小有关。治疗主要是手术切除。放疗已被证明可使局部切除后的复发率减半。涉及手术切除范围和放疗添加的治疗决策基于肿瘤大小、分级以及患者年龄等因素的考虑。
