Banchongaksorn T, Yomokgul P, Panyim S, Rooney W, Vickers P
Malaria Centre Region 2, Amphur Muang, Chiang Mai, Thailand.
Trans R Soc Trop Med Hyg. 1996 May-Jun;90(3):244-5. doi: 10.1016/s0035-9203(96)90231-x.
The rapid manual ParaSight-F test for Plasmodium falciparum is an antigen capture test detecting trophozoite-derived histidine rich protein II, is simple and provides a definitive diagnosis within 10 min. Compared with 913 thick blood film examinations, the ParaSight-F test had 93.4% sensitivity and 98.2% specificity. Compared with 520 blood samples within the same study examined with the aid of the polymerase chain reaction, the ParaSight-F test had 91.6% sensitivity and 99.4% specificity. The ParaSight-F test could be a valuable diagnostic tool for falciparum malaria in any situation requiring rapid diagnosis in the absence of microscopical examination.
用于检测恶性疟原虫的快速手动ParaSight-F试验是一种抗原捕获试验，可检测滋养体衍生的富含组氨酸蛋白II，操作简单，可在10分钟内做出明确诊断。与913次厚血膜检查相比，ParaSight-F试验的灵敏度为93.4%，特异性为98.2%。在同一研究中，与借助聚合酶链反应检测的520份血样相比，ParaSight-F试验的灵敏度为91.6%，特异性为99.4%。在任何需要快速诊断且无法进行显微镜检查的情况下，ParaSight-F试验可能是诊断恶性疟的一种有价值的诊断工具。
