Xiang Y, Sun N, Chang X, Bian X, Wang F
Peking Union Medical College Hospital, PUMC & CAMS, Beijing.
Chin Med J (Engl). 1996 Apr;109(4):291-4.
To evaluate the efficacy and safety of cordocentesis for prenatal diagnosis of various fetal diseases.
Fetal blood sampling was performed in 30 pregnancies from gestational week 19 to 36 for various prenatal diagnoses. We used Aloka SSD-650 real-time ultrasound scanner with 3.5 mHz curvilinear transducer during the procedure. A regular 22-gauge spinal needle was used for fetal blood sampling.
Twenty-five cordocentesis were successful at the first attempt. A second attempt of cordocentesis succeeded in three cases. In the remaining two cases, intrahepatic vein sampling and cardiocentesis were employed respectively. The duration of procedure was shorter than 15 minutes in 25 cases. 1-6 ml of fetal blood was obtained from each case. Fetal blood was diluted with amniotic fluid in four samples. Maternal blood contamination never happened. No lethal complication occurred in our series.
It is believed that cordocentesis is a safe and useful method for prenatal diagnosis, and intrahepatic vein sampling is an alternative choice when cordocentesis has failed.
评估脐静脉穿刺术对各种胎儿疾病进行产前诊断的有效性和安全性。
对30例妊娠19至36周的孕妇进行胎儿血样采集以进行各种产前诊断。操作过程中我们使用配备3.5兆赫兹曲线探头的阿洛卡SSD - 650实时超声扫描仪。使用常规的22号脊椎穿刺针进行胎儿血样采集。
25例脐静脉穿刺术首次尝试成功。3例第二次尝试成功。其余2例分别采用肝内静脉采血和心脏穿刺术。25例操作时间短于15分钟。每例获取1 - 6毫升胎儿血液。4份样本中胎儿血液被羊水稀释。未发生母体血液污染。本系列未发生致命并发症。
据信脐静脉穿刺术是一种安全且有用的产前诊断方法，当脐静脉穿刺术失败时肝内静脉采血是一种替代选择。
