Wu T, Wang S L, Xiang Y Z
Sanitary and Anti-epidemic Station, Zhejiang Province, Hangzhou.
Zhonghua Liu Xing Bing Xue Za Zhi. 1996 Apr;17(2):70-2.
Through observation to subclinical infection of the 71 children who had been inoculated against measles 12 years ago and then exposed to natural measles from three classes at a primary school, we have noticed: (1) Subclinical infection did exist among the crowd who were inoculation against measles; The rate of subclinical infection of the three classes was between 18.5%-75.0%, with an average of 45.1%. (2) The level of the HI Ab titer was between 1:2-1:16. The peak level was between 1:2 and/or 1:4. So the rate of subclinical infection who had been inoculation against measles but later exposed to natural measles would depend on the proportion of those whose titer of HI Ab was 1:2-1:4 in the crowd. (3) The epidemiological significance of subclinical measles infection lies in that it can actively keep and consolidate the level of immunity to certain extent in a crowd who had been inoculation against measles.
通过对12年前接种过麻疹疫苗、后在某小学三个班级接触自然麻疹的71名儿童的亚临床感染情况进行观察，我们注意到：（1）接种过麻疹疫苗的人群中确实存在亚临床感染；三个班级的亚临床感染率在18.5%-75.0%之间，平均为45.1%。（2）HI抗体滴度水平在1:2-1:16之间。峰值水平在1:2和/或1:4之间。因此，接种过麻疹疫苗但后来接触自然麻疹的亚临床感染率将取决于人群中HI抗体滴度为1:2-1:4者的比例。（3）亚临床麻疹感染的流行病学意义在于，它能在一定程度上主动维持和巩固接种过麻疹疫苗人群的免疫水平。
