Hu Y H, Li L M, Li P
Department of Epidemiology, Beijing Medical University.
Zhonghua Liu Xing Bing Xue Za Zhi. 1996 Feb;17(1):20-4.
A total number of 167,274 births were observed on birth defects in rural areas 1968-1990 in China. The results showed that there were 361 cases of neural system defects, accounting for 31.45% in all birth defects. The incidence of neural system defects was 2.19% with hydrocephalus, anencephalus and spinal bifida 0.89%, 0.87%, 0.36% respectively. The distribution of neural system birth defects showed that incidence in northern part of the country was higher than that of in the south while in winter--spring was higher than in summer--autumn. Results of unconditional logistic regression analysis demonstrated that risk factors were related to neural system defects as maternal education level, parity, delivery mode and lower birth weight.
1968年至1990年期间，在中国农村地区共观察到167274例出生缺陷病例。结果显示，神经系统缺陷病例有361例，占所有出生缺陷的31.45%。神经系统缺陷的发病率为2.19%，其中脑积水、无脑儿和脊柱裂的发病率分别为0.89%、0.87%、0.36%。神经系统出生缺陷的分布显示，该国北部的发病率高于南部，冬季至春季高于夏季至秋季。无条件逻辑回归分析结果表明，危险因素与神经系统缺陷有关，如母亲教育水平、产次、分娩方式和低出生体重。
