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[腹腔镜下胆总管结石的治疗。189例患者的前瞻性多中心研究]

[Treatment of common bile duct lithiasis under laparoscopy. A prospective multicenter study in 189 patients].

作者信息

Millat B, Deleuze A, Atger J, Briandet H, Fingerhut A, Marrel E, de Seguin C, Soulier P

机构信息

Départment de Chirurgie Digestive A, Hôpital Saint-Eloi, Montpellier.

出版信息

Gastroenterol Clin Biol. 1996;20(4):339-45.

PMID:8758499
Abstract

OBJECTIVES

The aim of this study was to assess the feasibility and results of common bile duct laparoscopic treatment and exploration in patients with choledocholithiasis.

PATIENTS AND METHODS

From November 1991 to December 1994, 189 consecutive malades (120 females; mean age 68 years, range: 21-92) with choledocholithiasis identified during routine intraoperative cholangiogram underwent surgical exploration of common bile duct in 5 surgical centers. Twenty patients were referred to surgery after unsuccessful endoscopic sphincterotomy.

RESULTS

Following laparoscopic exploration and intraoperative cholangiography, common bile duct stone extraction by laparoscopy was not attempted in 11 patients (5.8%). The common bile duct was successfully cleared of all stones in 153 patients (81% of the overall population and 86% of laparoscopic attempts), either via the transcystic route (n = 97) or through choledocotomy (n = 56). Eighteen patients required conversion to open surgery, 16 for unsuccessful stone extraction and 2 despite successful stone extraction. Postoperative endoscopic sphincterotomy was required in 7 patients (4.4%) for retained stones after laparoscopic treatment. There were no postoperative deaths (95% confidence interval 0-1.6%), and follow-up, ranging from 3 to 42 months, has shown no further clinical evidence of retained stones.

CONCLUSION

Diagnosis and treatment of common bile duct stones is feasible by laparoscopy, and the results in this series compare favorably with those of conventional surgical treatment. Complete treatment of biliary lithiasis, in one operation, avoids the pitfalls of patient selection for preoperative endoscopic retrograde cholangiography and the risks of endoscopic sphincterotomy.

摘要

目的

本研究旨在评估胆总管结石患者行腹腔镜胆总管治疗及探查的可行性和效果。

患者与方法

1991年11月至1994年12月,5个手术中心对189例(120例女性;平均年龄68岁,范围:21 - 92岁)在术中常规胆管造影时确诊为胆总管结石的患者进行了胆总管手术探查。20例患者在内镜括约肌切开术失败后转诊接受手术。

结果

在腹腔镜探查及术中胆管造影后,11例患者(5.8%)未尝试通过腹腔镜取胆总管结石。153例患者(占总人数的81%,腹腔镜手术尝试患者的86%)通过经胆囊途径(n = 97)或胆总管切开术(n = 56)成功清除了胆总管内所有结石。18例患者需要转为开腹手术,16例因取石失败,2例尽管取石成功。7例患者(4.4%)在腹腔镜治疗后因残留结石需要行术后内镜括约肌切开术。无术后死亡病例(95%置信区间0 - 1.6%),随访3至42个月,未发现残留结石的进一步临床证据。

结论

腹腔镜诊断和治疗胆总管结石是可行的,本系列结果与传统手术治疗结果相比具有优势。一次手术完成胆管结石的彻底治疗,避免了术前内镜逆行胆管造影患者选择的缺陷以及内镜括约肌切开术的风险。

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