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[Hypomagnesemic and hypocalcemic coma, convulsions and ocular motility disorders after chemotherapy with platinum compounds].

作者信息

Bachmeyer C, Decroix Y, Médioni J, Dhôte R, Benfiguig K, Houillier P, Grateau G

机构信息

Service de médecine interne, hôpital Hôtel-Dieu, Paris, France.

出版信息

Rev Med Interne. 1996;17(6):467-9. doi: 10.1016/0248-8663(96)86439-3.

Abstract

We describe a case of neurologic manifestations including coma, convulsion and eye movement disorders, associated with hypomagnesemia and hypocalcemia in a patient treated with cisplatin for an ovarian adenocarcinoma. Pathophysiological mechanisms involve renal tubular damage leading to renal magnesium wasting and related hypocalcemia.

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